現職
亞東紀念醫院醫學研究部 研究員 (2022.04-)
核心實驗室
突觸傳遞及神經藥理實驗室
經歷
亞東紀念醫院心血管中心 研究員 (2009.08-2022.03)
學歷
Biology Science, University of Warwick,UK Ph.D
國立陽明大學微生免疫所 碩士
專長領域
神經細胞生理、神經突觸調控機制
個人著作
Lu, C.W.; Lin, C.J.; Hsieh, P.W.; Chiu, K.M.; Lee, M.Y.; Lin, T.Y.; Wang, S.J. An Anthranilate Derivative Inhibits Glutamate Release and Glutamate Excitotoxicity in Rats. Int J Mol Sci 2022, 23, doi:10.3390/ijms23052641. (IF: 5.924) Lin, T.-Y.; Chen, I.-Y.; Lee, M.Y.; Lu, C.-W.;Chiu, K.M.; Wang, S.-J. Inhibition of Glutamate Release from Rat Cortical Nerve Terminals by Dehydrocorydaline, an Alkaloid from Corydalis yanhusuo. Molecules 2022, 27, 960. (IF: 4.421) Lu, C.W.; Lin, T.Y.; Pan, T.L.; Wang, P.W.; Chiu, K.M.; Lee, M.Y.; Wang, S.J. Asiatic Acid Prevents Cognitive Deficits by Inhibiting Calpain Activation and Preserving Synaptic and Mitochondrial Function in Rats with Kainic Acid-Induced Seizure. Biomedicines 2021, 9, doi:10.3390/biomedicines9030284. (IF: 6.081) Lu, C.W.; Lin, T.Y.; Huang, S.K.;Chiu, K.M.; Lee, M.Y.; Huang, J.H.; Wang, S.J. Inhibition of glutamatergic transmission and neuronal excitability by oxycodone in the rat hippocampal CA3 neurons. Can J Physiol Pharmacol 2021, 99, 737-743, doi:10.1139/cjpp-2020-0469. (IF: 2.273) Lu, C.W.; Huang, Y.C.;Chiu, K.M.; Lee, M.Y.; Lin, T.Y.; Wang, S.J. Enmein Decreases Synaptic Glutamate Release and Protects against Kainic Acid-Induced Brain Injury in Rats. Int J Mol Sci 2021, 22, doi:10.3390/ijms222312966. (IF: 5.924) Lin, T.Y.; Lu, C.W.; Hsieh, P.W.;Chiu, K.M.; Lee, M.Y.; Wang, S.J. Natural Product Isoliquiritigenin Activates GABA(B) Receptors to Decrease Voltage-Gate Ca(2+) Channels and Glutamate Release in Rat Cerebrocortical Nerve Terminals. Biomolecules 2021, 11, doi:10.3390/biom11101537. (IF: 6.081) Chiu, K.M.; Lin, T.Y.; Lee, M.Y.; Lu, C.W.; Wang, M.J.; Wang, S.J. Typhaneoside Suppresses Glutamate Release Through Inhibition of Voltage-Dependent Calcium Entry in Rat Cerebrocortical Nerve Terminals. Chem Res Toxicol 2021, 34, 1286-1295, doi:10.1021/acs.chemrestox.0c00446. (IF: 3.739) Lu, C.W.; Lin, T.Y.; Chiu, K.M.; Lee, M.Y.; Huang, J.H.; Wang, S.J. Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats. Biomedicines 2020, 8, doi:10.3390/biomedicines8110486. (IF: 6.081) Chiu, K.M.; Lin, T.Y.; Lee, M.Y.; Lu, C.W.; Wang, M.J.; Wang, S.J. Dexmedetomidine protects neurons from kainic acid-induced excitotoxicity by activating BDNF signaling. Neurochem Int 2019, 129, 104493, doi:10.1016/j.neuint.2019.104493. (IF: 3.921) Chiu, K.M.; Lin, T.Y.; Lee, M.Y.; Lu, C.W.; Wang, M.J.; Wang, S.J. Ropivacaine Protects against Memory Impairment and Hippocampal Damage in a Rat Neurodegeneration Model. Pharmacology 2018, 102, 307-315, doi:10.1159/000493145. (IF: 2.547) Chiu, K.M.; Lu, C.W.; Lee, M.Y.; Wang, M.J.; Lin, T.Y.; Wang, S.J. Neuroprotective and anti-inflammatory effects of lidocaine in kainic acid-injected rats. Neuroreport 2016, 27, 501-507, doi:10.1097/wnr.0000000000000570. (IF: 1.837) Chiu, K.M.; Wu, C.C.; Wang, M.J.; Lee, M.Y.; Wang, S.J. Protective effects of bupivacaine against kainic acid-induced seizure and neuronal cell death in the rat hippocampus. Biol Pharm Bull 2015, 38, 522-530, doi:10.1248/bpb.b14-00633. (IF: 2.233)
醫學研究部研究員 李明怡 博士
(Ming-Yi Lee, PhD.)
E-mail:mingyi-lee@mail.femh.org.tw (分機4566)