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1. Tsan-Chi Chen, Wan-Lin Wu, Shu-Wen Chang*. Persistent loss of membrane-associated MUC4 reprograms physiological functions in corneal epithelial cells via MAPK-dependent cascade. Sci Rep. 2026 May 27;16(1):24118. doi: 10.1038/s41598-026-54944-9. [IF: 4.9; 21/140 (15.0%) in Multidisciplinary Sciences] (³sµ²)
2. Min-Po Ho, Yuan-Hui Wu, Tsan-Chi Chen, Kuang-Chau Tsai, Chen-Chang Yang*, Feng-Yuan Chu*. Relationship between cardiovascular disease risk and long-2 term neurological sequelae after carbon monoxide poisoning: a 3 nationwide cohort study. J. Clin. Med. 2026, Mar 18;15(6):2338. doi: 10.3390/jcm15062338. [IF: 3.3; 67/336 (19.9%) in Medicine, General & Internal] (³sµ²)
3. Min-Po Ho, Yuan-Hui Wu, Tsan-Chi Chen, Kuang-Chau Tsai, Chen-Chang Yang. Potential risk factors for delayed neurological sequelae and myocardial injury following acute carbon monoxide poisoning: A retrospective study. J Chin Med Assoc. 2025 Apr 1; 88(4):330-337. doi: 10.1097/JCMA.0000000000001208. Epub 2025 Jan 16. [IF: 2.3; 99/336 (29.5%) in Medicine, General & Internal] (³sµ²)
4. Wei-Ting Ho, Jung-Shen Chang, Chia-Jen Lei, Tsan-Chi Chen, Jia-Kang Wang, Shu-Wen Chang, Muh-Hwa Yang, Tzuu-Shuh Jou, I-Jong Wang. ROCK Inhibitor Enhances Resilience Against Metabolic Stress Through Increasing Bioenergetic Capacity in Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2025 Jan 2; 66(1):51. doi: 10.1167/iovs.66.1.51. [IF: 5.5; 10/98 (10.2%) in Ophthalmology] (³sµ²)
5. Tsan-Chi Chen, Shu-Wen Chang*. Non-lethal exposure to short-wavelength light-emitting diodes modulates tight-junction structure in human corneal epithelial cells via cAMP-dependent signaling. J Photochem Photobiol B. 2024 May; 252:112869. [IF: 4.0; 19/81 (23.5%) in Biophysics] (³sµ²)
6. Hsiu-Ling Chou, Tsan-Chi Chen, Chung-Tay Yao. Comparing the sensitivity of fatigue and sleep disturbance assessment tools in women with advanced cancer undergoing chemotherapy. Asia-Pac J Oncol Nurs. 2024 Feb; 11(2):100331. [IF: 3.3; 24/194 (12.4%) in Nursing] (³sµ²)
7. Yuan-Hui Wu, Ai-Hsien Li, Tsan-Chi Chen, Jen-Kuei Liu, Kuang-Chau Tsai, Min-Po Ho. Compared with Physician Overread, Computer Is Less Accurate but Helpful in Interpretation of Electrocardiography for ST-segment Elevation Myocardial Infarction. Journal of Electrocardiology 2023 Nov-Dec; 81:60-65 [IF: 1.5; 162/237 (68.4%) in Cardiac & Cardiovascular Systems] (³sµ²)
8. Pen-Chih Liao, Ming-Shu Chen, Mao-Jhen Jhou Tsan-Chi Chen, Chih-Te Yang, Chi-Jie Lu*. Integrating Health Data-Driven Machine Learning Algorithms to Evaluate Risk Factors of Early-Stage Hypertension at Different Levels of HDL and LDL Cholesterol. Diagnostics (Basel) 2022 Aug 14; 12(8):1965; doi: 10.3390/diagnostics12081965 [IF: 3.8; 61/336 (18.2%) in Medicine, General & Internal] (³sµ²)
9. Wei-Ting Ho, Jung-Shen Chang, Tsan-Chi Chen., Jia-Kang Wang, Shu-Wen Chang, Muh-Hwa Yang, Tzuu-Shuh Jou*, I-Jong Wang*. Inhibition of Rho-associated protein kinase activity enhances oxidative phosphorylation to support corneal endothelial cell migration. FASEB J 2022 Jul; 36(7):e22397. doi: 10.1096/fj.202101442RR. [IF: 4.3; 19/106 (17.9%) in Biology] (³sµ²)
10. Tsan-Chi Chen, Shu-Wen Chang*. Repeated cell sorting ensures the homogeneity of ocular cell populations expressing a transgenic protein. PLoS ONE 2022; 17(3):e0265183. doi: 10.1371/journal.pone.0265183. eCollection 2022. [IF: 2.8; 48/140 (34.3%) in Multidisciplinary Sciences] (³sµ²)
11. Rai-Hua Lai, Yen-Hung Chow, Nai-Hsiang Chung, Tsan-Chi Chen, Feng-Shiun Shie*, Jyh-Lyh Juang*. Neurotropic EV71 causes encephalitis by engaging intracellular TLR9 to elicit neurotoxic IL12-p40-iNOS signaling. Cell Death Dis. 2022; 13(4):328. doi: 10.1038/s41419-022-04771-3. [IF: 12.2; 27/207 (13.0%) in Cell Biology] (³sµ²)
12. Tsan-Chi Chen, Shu-Wen Chang*. Moxifloxacin induces random migration in human corneal fibroblasts via the protein kinase C epsilon/zonula occludens-1 signaling pathway. Eur J Pharmacol. 2021 Nov 5:910:174414. doi: 10.1016/j.ejphar.2021.174414. [IF: 5.7; 52/356 (14.6%) in Pharmacology & Pharmacy] (³sµ²)
13. Wen-Wen Zeng, Tsan-Chi Chen, Cheng-Huan Liu, Sheng-Yang Wang, Jei-Fu Shaw, Yu-Ting Chen*. Identification and Isolation of an Intermediate Metabolite with Dual Antioxidant and Anti-Proliferative Activity Present in the Fungus Antrodia cinnamomea Cultured on an Alternative Medium with Cinnamomum kanehirai Leaf Extract. Plants (Basel). 2021 Apr 9;10(4):737. [IF: 4.7; 46/285 (16.1%) in Plant Sciences] (³sµ²)
14. Tsan-Chi Chen, Wei-Ting Ho, Chien-Hsueh Lai, Shu-Wen Chang*. Mitomycin C modulates intracellular matrix metalloproteinase-9 expression and affects corneal fibroblast migration. Eur J Pharmacol. 2019 Dec 15;865:172752. [IF: 5.7; 52/356 (14.6%) in Pharmacology & Pharmacy]. (³sµ²)
15. Hsiu-Ling Chou, Tsu-Yi Chao, Tsan-Chi Chen, Chi-Ming Chu, Chen-Hsi Hsieh, Liang-In Lin, Chung-Tay Yao. Chemotherapy agents induce tartrateresistant acid phosphatase 5a contributing to the symptom distress in lung cancer patients. Eur J Pharmacol. 2019 Mar 5;846:38-48. [IF: 5.7; 52/356 (14.6%) in Pharmacology & Pharmacy]. (³sµ²)
16. Wei-Ting Ho, Jung-Shen Chang, Tsan-Chi Chen, San-Fang Chou, I-Jong Wang, Shu-Wen Chang*. Evaluation of patent blue as the vital dye in the animal model of Descemet Membrane Endothelial Keratoplasty. Cornea 2019 Mar;38(3):360-363. [IF: 2.3; 40/98 (40.8%) in Ophthalmology] (³sµ²)
17. Tsan-Chi Chen, Shu-Wen Chang*. Moxifloxacin Modulated TGF£]1-Related Interleukin-12 Secretion in Corneal Fibroblasts. Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5692-5702. [IF: 5.5; 10/98 (10.2%) in Ophthalmology] (³sµ²)
18. Hsiu-Ling Chou, Tsu-Yi Chao, Tsan-Chi Chen, Chi-Ming Chu, Chen-Hsi Hsieh, Chung-Tay Yao*, Anthony J. Janckila. The Relationship Between Inflammatory Biomarkers and Symptom Distress in Lung Cancer Patients Undergoing Chemotherapy. Cancer Nurs. 2017 Mar/Apr;40(2):E1-E8. [IF: 2.6; 44/194 (22.7%) in Nursing] (³sµ²)
19. Tsan-Chi Chen, Tzu-Yun Tsai, Shu-Wen Chang*. Molecular Mechanism of Fluoroquinolone Modulation on Corneal Fibroblast Motility. Exp Eye Res. 2016 Apr;145:10-16. [IF: 3.1; 25/98 (25.5%) in Ophthalmology](³sµ²)
20. Wei-Ting Ho, Tsan-Chi Chen (equal first), San-Fang Chou, Shu-Wen Chang*. Dexamethasone modifies mitomycin C-triggered interleukin-8 secretion in isolated human Tenon's capsule fibroblasts. Exp Eye Res. 2014 Jul;124:86-92. [IF: 3.1; 25/98 (25.5%) in Ophthalmology] (³sµ²)
21. Tsan-Chi Chen, Shu-Wen Chang*, Ting-Yi Wang. Moxifloxacin modifies corneal fibroblast-to-myofibroblast differentiation. Brit. J. Pharmacol. 2013 Mar; 168 (6): 1341-54. [IF: 7.5; 27/356 (7.6%) in Pharmacology & Pharmacy] (³sµ²)
22. Tsan-Chi Chen, Chien-Hsueh Lai,Jie-Ling Chang, Shu-Wen Chang*. Mitomycin C Retardation of Corneal Fibroblast Migration via Sustained Dephosphorylation of Paxillin at Tyrosine 118. Invest. Ophthalmol. Vis. Sci. 2012 Mar; 53 (3):1539-47. [IF: 5.5; 10/98 (10.2%) in Ophthalmology] (³sµ²)
23. Tsan-Chi Chen, Shu-Wen Chang*. Effect of Mitomycin C on IL-1R Expression, IL-1-Related Hepatocyte Growth Factor Secretion and Corneal Epithelial Cell Migration. Invest. Ophthalmol. Vis. Sci. 2010 Mar; 51 (3):1389-96. [IF: 5.5; 10/98 (10.2%) in Ophthalmology] (³sµ²)
24. Tsan-Chi Chen, Yiu-Kay Lai, Chun-Keung Yu, Jyh-Lyh Juang*. Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signaling. Cell. Microbiol. 2007 Nov; 9:2676-88. [IF: 2.6; 11/167 (67.1%) in Microbiology] (³sµ²)
25. Tsan-Chi Chen, Guang-Wu Chen, Chao Agnes Hsiung, Jyh-Yuan Yang, Shin-Ru Shih, Yiu-Kay Lai, Jyh-Lyh Juang*. Combining multiplex reverse transcription-PCR and a diagnostic microarray to detect and differentiate enterovirus 71 and coxsackievirus A16. J. Clin. Microbiol.2006 Jun; 44: 2212-9. [IF: 5.9; 31/167 (18.6%) in Microbiology] (³sµ²)
26. Chien-Wen Chen, Tzu-Yang Lin, Tsan-Chi Chen (eqaul second) , Jyh-Lyh Juang*. Distinct translation regulation by two alternative 5'UTRs of a stress-responsive protein--dPrx I. J. Biomed. Sci. 2005 Oct; 12(5):729-39. [IF: 14.5; 8/191 (4.2%) in Medicine, Research & Experimental] (³sµ²)
27. Jyh-Lyh Juang*, Tsan-Chi Chen, Shih Sheng Jiang, Chao A Hsiung, Wei-Chen Chen, Guang-Wu Chen, Shiang-Ming Lin, Jih-Hui Lin, Shu-Chun Chiu, Yiu-Kay Lai. Coupling multiplex RT-PCR to a gene chip assay for sensitive and semi-quantitative detection of severe acute respiratory syndrome-coronavirus. Lab. Invest. 2004 Sep; 84 (9): 1085-91. [IF: 4.1; 13/89 (14.6%) in Pathology] (³sµ²)
28. Shih Sheng Jiang, Tsan-Chi Chen, Jyh-Yuan Yang, Chao A Hsiung, Ih-Jen Su, Ying-Lan Liu, Po-Cheng Chen, Jyh-Lyh Juang*. Sensitive and quantitative detection of severe acute respiratory syndrome coronavirus infection by real-time nested polymerase chain reaction. Clin. Infect. Dis. 2004 Jan; 38 (2):293-6. [IF: 8.3; 8/14 (5.7%) in Infectious Diseases] (³sµ²)

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1. Shu-Wen Chang, Tsan-Chi Chen. Tacrolimus and sirolimus enhanced the regulation of intracellular signaling pathways in human corneal epithelial cells through MUC4 deficiency. 2026 Mid-year Scientific Meeting of Taiwan Academy of Ophthalmology & the Ophthalmolgical Society of Taiwan, Taichung, Taiwan. June 27-28, 2026.
2. Tsan-Chi Chen, Shu-Wen Chang, Wei-Ting Ho, Wan-Lin Wu. Negative regulatory effect of intracellular fatty acid-binding protein-5 deficiency on the motility of human corneal epithelial cells. American Physiology Summit 2026, Minneapolis, MN, U.S.A. Apr 22-26, 2026.
3. Shu-Wen Chang, Tsan-Chi Chen. S100A9 deficiency inhibits the migration of human corneal epithelial cells by controlling multiple cellular regulatory mechanisms. The 66th Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Dec 13-14, 2025.
4. Shu-Wen Chang, Tsan-Chi Chen. MUC4 regulated intracellular network via mitochondrial signaling in corneal and conjunctival epithelial cells. ADES 2025 in Conjunction with KDES, Jeju, Korea. May 30-31, 2025.
5. Shu-Wen Chang, Tsan-Chi Chen. Diquafosol modulates mitochondrial metabolic function in human corneal epithelial cells via a MUC4-regulating mechanism. 2025 Mid-year Scientific Meeting of Taiwan Academy of Ophthalmology & the Ophthalmolgical Society of Taiwan, Taichung, Taiwan. May 17-18, 2025.
6. Shu-Wen Chang, Tsan-Chi Chen. MUC4 regulated intracellular network via mitochondrial signaling in corneal and conjunctival epithelial cells. 2025 Annual Meeting of the Association of Research in Vision and Ophthalmology, Salt Lake, U.S.A. May 4-8, 2025.
7. Tsan-Chi Chen, Shu-Wen Chang. Differences in the wavelength-dependent photobiomodulation of monochromatic light-emitting diodes on various ocular cells. American Physiology Summit 2025, Baltimore, MD, U.S.A. Apr 24-27, 2025.
8. Shu-Wen Chang, Tsan-Chi Chen, Wei-Ting Ho. Fatty acid-binding protein-5 deficiency suppresses motility in human corneal epithelial cells. The 65th Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 16-17, 2024.
9. Tsan-Chi Chen, Shu-Wen Chang, Wei-Ting Ho. Non-lethal monochromatic LEDs trigger potential intracellular signaling cascades in human corneal fibroblasts according to next-generation sequencing and ingenuity pathway analysis. Biomolecular Horizons 2024, Melbourne, Australia. Sep 22-25, 2024.
10. Shu-Wen Chang, Tsan-Chi Chen. Palmitic acid hydroxy stearic acids activate intracellular signals and modulate cell viability in human corneal epithelial cells. 2024 Mid-year Scientific Meeting of Taiwan Academy of Ophthalmology & the Ophthalmolgical Society of Taiwan, Tainan, Taiwan. June 1-2, 2024.
11. Shu-Wen Chang, Tsan-Chi Chen. MUC4 on human ocular epithelial cells contributed to activation of the intracellular signaling networks by cytokines and chemoattractants. The 64th Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 18-19, 2023.
12. Shu-Wen Chang, Tsan-Chi Chen. Long-term cultivation might modulate the membrane-associated mucins in human corneal epithelial cells. 2023 Mid-year Scientific Joint Meeting of The Ophthalmological Society of Taiwan and Taiwan Academy of Ophthalmology, Kaohsiung, Taiwan. June 10-11, 2023.
13. Shu-Wen Chang, Wei-Ting Ho, Tsan-Chi Chen. Intracellular FABP5 suppresses cytokine-regulated gene expression in human corneal epithelial cells via G-protein coupled receptor-mediated protein translation. The 63rd Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 19-20, 2022.
14. Shu-Wen Chang, Tsan-Chi Chen. Investigation of inflammatory gene responses following exposure to non-lethal monochromatic LEDs in human corneal fibroblasts using next-generation sequencing and ingenuity pathway analysis. 2022 Mid-year Scientific Meeting of the Ophthalmological Society of Taiwan, Panciao, New Taipei City, Taiwan. May 14-15, 2022.
15. Shu-Wen Chang, Tsan-Chi Chen. MUC4 modulates the interleukin-17F-induced gene expressions in ocular epithelial cells via G-protein-mediated signaling mechanism. The 62nd Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Dec 4-5, 2021.
16. Shu-Wen Chang, Tsan-Chi Chen. Low exposures to monochromatic LED modulate different subcellular mechanisms in human ocular epithelial cells using next-generation sequencing and ingenuity pathway analysis. The 62nd Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Dec 4-5, 2021. (²´¬ì110¦~²Ä62¦¸¦~«×Âå¾Ç·|¡mÀu¨q¾À³ø½×¤å¼ú¡n-»ÉµP)
17. Shu-Wen Chang, Tsan-Chi Chen. Hyaluronic acid suppresses monochromatic LED-induced IL-6 and IL-8 secretions in human corneal epithelial cells via CD44/RIP3/PTEN pathway. 2021 Mid-year Scientific Meeting of the Ophthalmological Society of Taiwan, Koahsiung, Taiwan. Apr 10-11, 2021.
18. Shu-Wen Chang, Tsan-Chi Chen. Importance of MUC4 in human ocular epithelial cells using next generation sequencing (NGS) and ingenuity pathway analysis (IPA). 2021 Mid-year Scientific Meeting of the Ophthalmological Society of Taiwan. Koahsiung Taiwan, Apr 10-11, 2021.
19. Shu-Wen Chang, Tsan-Chi Chen. Interleukin-17F modulates intracellular gene expressions in ocular cells using next generation sequencing (NGS) and ingenuity pathway analysis (IPA). 2021 Mid-year Scientific Meeting of the Ophthalmological Society of Taiwan, Koahsiung. Apr 10-11, 2021.
20. Shu-Wen Chang, Tsan-Chi Chen. Coenzyme Q10 suppresses LED-induced cytokine expressions in human corneal epithelial cells via modulating Bax dimerization. The 61st Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 21-22, 2020.
21. Shu-Wen Chang, Tsan-Chi Chen. Moxifloxacin induces random migration in human corneal fibroblasts via PKC£`/ZO-1 signaling pathway. The 61st Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 21-22, 2020.
22. Shu-Wen Chang, Tsan-Chi Chen, Che-Wei Lee. Repeated cell sorting contributes to persistent expression of the exogenous proteins in ocular cells. The 61st Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Nov 21-22, 2020.
23. Shu-Wen Chang, Tsan-Chi Chen, Che-Wei Lee. Interleukin-17F Modulates the Secretory Cytokines in Ocular Surface Cells. The 60th Annual Meeting of the Ophthalmological Society of Taiwan, Taipei, Taiwan. Dec 13-15, 2019.
24. Tsan-Chi Chen, Shu-Wen Chang. Mitomycin C-Triggering Nuclear Translocation of Fibulin-1 Contributes to Gene Reduction in Human Corneal Fibroblasts by Microarray Analysis. 2019 Annual Meeting of the Association of Research in Vision and Ophthalmology, Vancouver, Canada. Apr 28-May 2, 2019.
25. Shu-Wen Chang, Tsan-Chi Chen. Coenzyme Q10 Prevents the Monochromatic LED Related FAK/Paxillin Suppression in Human Lens Epithelial Cell Migration. The 59th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Nov 17-18, 2018.
26. Shu-Wen Chang, Tsan-Chi Chen. Maintenance of Intracellular FAK Expression Contributes to the Tolerance to Monochromatic LED Light Exposure. The 36th World Ophthalmology CongressR (WOC) of the International Council of Ophthalmology, Barcelona, Spain. June 16-19, 2018.
27. Shu-Wen Chang, Tsan-Chi Chen. LEDs Modulate Tight-Junction Formation in Human Corneal Epithelial Cells via Intracellular cAMP Level. The 2018 Annual Meeting of the Association of Research in Vision and Ophthalmology (ARVO), Honolulu, Hawaii, U.S.A. Apr 29-May 3, 2018.
28. Tsan-Chi Chen, Shu-Wen Chang. Monochromatic LEDs Modulate Mucins Expression in Human Corneal Epithelial Cells. The 33rd Asia-Pacific Academy of Ophthalmology (APAO) Congress in conjunction with the 29th Hong Kong Ophthalmological Symposium, Hong Kong. Feb 8-11, 2018.
29. Shu-Wen Chang, Tsan-Chi Chen. Short-Wavelength Monochromatic LED Enhanced Tight-Junction Formation in Human Corneal Epithelial Cells. The 33rd Asia-Pacific Academy of Ophthalmology (APAO) Congress in conjunction with the 29th Hong Kong Ophthalmological Symposium, Hong Kong, Feb 8-11, 2018.
30. Shu-Wen Chang, Tsan-Chi Chen. Short-Wavelength Monochromatic LED Exposure Promotes Tight-Junction Formation in Human Corneal Epithelial Cells. The 58th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Nov 18-19, 2017.
31. Shu-Wen Chang, Tsan-Chi Chen. Effect of Monochromatic LED Exposure on Corneal Fibroblast Cell Migration. The 52st Regional Meeting of the Ophthalmological Society of the Republic of China, Taichung, Taiwan. Apr 15-16, 2017.
32. Shu-Wen Chang, Tsan-Chi Chen. Moxifloxacin Modulates Interleukin-12 Secretion in Corneal Fibroblasts. The 5th Asia Cornea Society Biennial Scientific Meeting (ACS 2016), Seoul, Korea. Dec 9-11, 2016. (Oral)
33. Shu-Wen Chang, Tsan-Chi Chen. Individual variation of IL-12 secretion in human corneal fibroblasts. The 51st Regional Meeting of the Ophthalmological Society of the Republic of China, Koahsiung, Taiwan. Nov 12-13, 2016.
34. Shu-Wen Chang, Tsan-Chi Chen. Difference in Corneal Cells and Lens Cells Tolerance to Monochromatic LED-Generated Lights. The 51st Regional Meeting of the Ophthalmological Society of the Republic of China, Koahsiung, Taiwan. Nov 12-13, 2016.
35. Wen-Wen Zeng, Tsan-Chi Chen, Sheng-Yang Wang, Cheng-Huan Liu, Yu-Ting Chen*: Identification of an anti-proliferative 2,4-dimethoxy-6-methylbenzene- 1,3-diol from Antrodia cinnamomea. 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology. Koahsiung, Taiwan. Nov 2-4, 2016.
36. Tsan-Chi Chen, Shu-Wen Chang. Improvement Efficiency of Human Corneal Fibroblast-Derived iPS Cells through Cell Sorting. The 31st Asia-Pacific Academy of Ophthalmology Congress (2016 APAO Taipei) held in conjunction with the 57th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Mar 24-27, 2016.
37. Tsan-Chi Chen, Shu-Wen Chang, I-Yu Chen, Fang-Yu Hsu. Modulation of Lens Fibrosis and Inflammation Response by Fluoroquinolones. The 31st Asia-Pacific Academy of Ophthalmology Congress (2016 APAO Taipei) held in conjunction with the 57th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Mar 24-27, 2016.
38. Shu-Wen Chang, Tsan-Chi Chen. Cellular Responses of Lens Epithelial Cells to Light-Emitting Diode-Generated Lights. The 31st Asia-Pacific Academy of Ophthalmology Congress (2016 APAO Taipei) held in conjunction with the 57th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Mar 24-27, 2016. (Oral)
39. Shu-Wen Chang, Tsan-Chi Chen, Ruo-Wei Hong, San-Fang Chou. Moxifloxacin Modulation of COX-2 Expression Contributes to Secrete Interleukin-8 in Corneal Fibroblasts. The 31st Asia-Pacific Academy of Ophthalmology Congress (2016 APAO Taipei) held in conjunction with the 57th Annual Meeting of the Ophthalmological Society of Chinese Taipei, Taipei, Taiwan. Mar 24-27, 2016.
40. Shu-Wen Chang, Tsan-Chi Chen. Moxifloxacin Retards Human Corneal Fibroblast Migration via ZO-1-Dependent Modulation. World Ophthalmology Congress of the International Council of Ophthalmology, Guadalajara, Mexico. Feb 5-9, 2016. (Oral)
41. Shu-Wen Chang, Tsan-Chi Chen, Ruo-Wei Hong, San-Fang Chou. Moxifloxacin Inhibits IL-8 Secretion in Corneal Fibroblasts via Diminishing COX-2 Expression. The 2015 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 28-29, 2015.
42. Shu-Wen Chang, Tsan-Chi Chen, I-Yu Chen, Fang-Yu Hsu. Fluoroquinolones Inhibit Lens Fibrosis and Inflammation Response in Human Lens Epithelial Cells. The 2015 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 28-29, 2015.
43. Shu-Wen Chang, Tsan-Chi Chen, I-Yu Chen. Efficient Isolation of Human Corneal Fibroblasts with Induced Pluripotent Stem Cell Genes. The 50th Regional Meeting of the Ophthalmological Society of the Republic of China, Kaohsiung, Taiwan. May 23-24, 2015.
44. Shu-Wen Chang, Tsan-Chi Chen. ABCG2 Expression Enhances Stem-Like Characters in Isolated Human Corneal Fibroblasts. The 2014 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Dec 13-14, 2014.
45. Tzu-Yun Tsai, Shu-Wen Chang, Tsan-Chi Chen. Fluoroquinolones modulate corneal fibroblast motility via changing the binding affinity of focal complex. The 2014 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Dec 13-14, 2014.
46. Shu-Wen Chang, Tsan-Chi Chen. ABCG2 Expression Enhances Stem-Like Characters in Isolated Human Corneal Fibroblasts. The 4th Asia Cornea Society Scientic Meeting, Taipei, Taiwan. Dec 11-12, 2014.
47. Tzu-Yun Tsai, Shu-Wen Chang, Tsan-Chi Chen. Fluoroquinolones modulate corneal fibroblast motility via changing the binding affinity of focal complex. The 4th Asia Cornea Society Scientic Meeting, Taipei, Taiwan. Dec 11-12, 2014.
48. Shu-Wen Chang, Tsan-Chi Chen, Han-Fang Teng, Chih-Chieh Lee, Pei-Hsiu Chiang. Mitomycin C Retards Corneal Fibroblast Cell Growth by Endogenous Fibulin-1 Expression. The Annual Meeting of the Association of Research in Vision and Ophthalmology, Orlando, Florida. U.S.A. May 4-8, 2014.
49. Shu-Wen Chang, Tsan-Chi Chen, Pei-Hsiu Chiang. Moxifloxacin Retards Human Corneal Fibroblast Migration via ZO-1-Dependent Modulation. The 49th Regional Meeting of the Ophthalmological Society of the Republic of China, Taichung, Taiwan. Apr 19-20, 2014.
50. Shu-Wen Chang, Tsan-Chi Chen, Chih-Chieh Lee, Han-Fang Teng. Moxifloxacin Suppresses Human Corneal Fibroblast Viability via Fibulin-1-Dependent Modulation. The 49th Regional Meeting of the Ophthalmological Society of the Republic of China, Taichung, Taiwan. Apr 19-20, 2014.
51. Shu-Wen Chang, Tsan-Chi Chen, Chih-Chieh Lee, Shin-Perng Wu. Moxifloxacin Inhibits Collagen I Secretion in Corneal Fibroblasts via Diminishing SNAP25 Expression. World Ophthalmolgy Congress of the International Council of Ophthalmology, Tokyo, Japan. Apr 2-6, 2014.
52. Shu-Wen Chang, Tsan-Chi Chen, Chih-Chieh Lee, Shin-Perng Wu. Moxifloxacin Inhibits Collagen I Secretion in Corneal Fibroblasts via Diminishing SNAP25 Expression. The 2013 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 30-Dec 1, 2013.
53. Shu-Wen Chang, Tsan-Chi Chen, Han-Fang Teng, Pei-Hsiu Chiang. Decreased Fibulin-1 Expression Contributed to Mitomycin C Retarded Corneal Fibroblasts Cell Growth. The 2013 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 30-Dec 1, 2013.
54. Tsan-Chi Chen, Shu-Wen Chang, Chih-Chieh Lee, Han-Fang Teng. Mitomycin C Suppresses Gene Splicing in Corneal Fibroblasts. The Annual Meeting of the Association of Research in Vision and Ophthalmology, Seattle, Washington, U.S.A. May 5-9, 2013. (2013 ARVO International Travel Grant) (NSC101-2320-B-418-002)
55. Shu-Wen Chang, Wei-Ting Ho, Tsan-Chi Chen, San-Fong Chou. Dexamethasone Modifies Viability of Mitomycin C-Treated Tenon¡¦s Fibroblasts. The annual meeting of the Association of Research in Vision and Ophthalmology, Seattle, Washington, U.S.A. May 5-9, 2013.
56. Shu-Wen Chang, Wei-Ting Ho, Tsan-Chi Chen, San-Fang Chou. Modification of Dexamethasone in Viability of Mitomycin C-Treated Tenon¡¦s Fibroblasts via Peroxisome Proliferator-Activated Receptor Gamma. Poster presented at the International Workshops on Granulomatous Uveitis and Ocular Behcet's Disease and Asia-Pacific Intraocular Inflammation Study Group, Kaohsiung, Taiwan, Apr 12-14, 2013.
57. Shu-Wen Chang, Tsan-Chi Chen, Hsia-Wei Liu, Kuei-Yen Tseng. Effect of Moxifloxacin-Modified IL-12 Secretion on Human Corneal Fibroblast Migration. Poster presented at the International Workshops on Granulomatous Uveitis and Ocular Behcet's Disease and Asia-Pacific Intraocular Inflammation Study Group, Kaohsiung, Taiwan, Apr 12-14, 2013.
58. Tsan-Chi Chen, Shu-Wen Chang, Chih-Chieh Lee, Han-Fang Teng. The Novel Role of Fibulin-1 as A Suppressor in Gene Splicing. The Twenty-first Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Pingtung, Taiwan. Jan 30-Feb 1, 2013.
59. Shu-Wen Chang, Tsan-Chi Chen. Effect of Fluoroquinolones in Corneal Fibroblast-to-Myofibroblast Differentiation. The 3rd Asia Cornea Society Biennial Scientific Meeting, Sofitel Philippine Plaza Hotal, Manila, Philippines. Nov 27-29, 2012.
60. Shu-Wen Chang, Tsan-Chi Chen, Chih-Chieh Lee, Han-Fang Tang. Characteristics of Reprogramming Human Corneal Fibroblasts with iPS Gene Expression. The 2012 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 17-18, 2012.
61. Kuei-Yen Tseng, Tsan-Chi Chen, Shu-Wen Chang*, Hsia-Wei Liu. The role of moxifloxacin for TGF-£]1-induced IL-12 secretion during corneal wound healing. The 2nd International Symposium of Materials on Regenerative Medicine, Taipei, Taiwan. Aug 29-31, 2012.
62. Shu-Wen Chang, Tsan-Chi Chen. Effect of Fluoroquinolones on Human Corneal Fibroblast Migration. ISER2012: XX Biennial Meeting of the International Society for Eye Research, Berlin, Germany. Jul 21-25, 2012.
63. Tsan-Chi Chen, Wei-Ting Ho, Hsiao-Wen Roan, Shu-Wen Chang*. Dexamethasone Rescues Mitomycin C-Suppressing Viability of Human Tenon¡¦s Fibroblasts via Bcl-2-Modulating Interleukin-8 Secretion. The 27th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. Mar 17-18, 2012.
64. Tsan-Chi Chen, Hsin-I Hsiau, Shu-Wen Chang*. Pluripotency of Human Corneal Fibroblasts under In Vitro Culture Condition. The 27th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. Mar 17-18, 2012.
65. Shu-Wen Chang, Tsan-Chi Chen. Mitomycin C-Inducing Assembly of Nuclear Fibulin-1 Protein in Human Corneal Fibroblasts. The 2011 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 26-27, 2011.
66. Shu-Wen Chang, Tsan-Chi Chen, Chuan-Long Hsu, Chien-Hsueh Lai. Mitomycin C Retards Corneal Fibroblast Cell Migration via Recruitment of FAK/Paxillin Complexes to Lamellipodial Matrix Metallopeptidase-9. The Association for Research in Vision and Ophthalmology's 2011 Annual Meeting, Fort Lauderdale, Florida, U.S.A. May 1-5, 2011. (NSC97-2314-B-418-005-MY3)
67. Tsan-Chi Chen, Chuan-Long Hsu, Hsiao-Wen Roan, Shu-Wen Chang*. Suppression of Mitomycin C on Gene Expression of Human Corneal Fibroblasts via Nuclear Fibulin-1 Assembly. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. Mar 19-20, 2011.
68. Tsan-Chi Chen, Hsin-I Hsiau, Chien-Hsueh Lai, Shu-Wen Chang*. Enhancement of ABCG2 in Human Corneal Fibroblasts using In Vitro Stimulating Culture System. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. Mar 19-20, 2011.
69. Shu-Wen Chang, Tsan-Chi Chen, Chien-Hsueh Lai. Mitomycin C Interferes in Matrix Metallopeptidase-9-Dependent Lamellipodial Extension of Corneal Fibroblasts. The 2010 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Dec 4-5, 2010.
70. Shu-Wen Chang, Tsan-Chi Chen, Pei-Ting Jian. Moxifloxacin Suppresses Corneal Fibroblast Cell Migration via Paxillin Dephosphorylation. The 2010 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Dec 4-5, 2010.
71. Shu-Wen Chang, Tsan-Chi Chen, Ting-Yi Wang, San-Fang Chou. Moxifloxacin Suppresses Myofibroblast Differentiation via Blocking TGF-betaRI on Corneal Fibroblasts. The Association for Research in Vision and Ophthalmology's 2010 Annual Meeting, Fort Lauderdale, Florida, U.S.A. May 2-6, 2010. (NSC97-2314-B-418-005-MY3)
72. Tsan-Chi Chen, Ting-Yi Wang, Chien-Hsueh Lai, Jie-Ling Chang, Shu-Wen Chang*. Mitomycin C-Retarding Corneal Fibroblast Migration via Dephosphorylation of Paxillin at Tyrosine 118. The 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan, Mar 27-28, 2010.
73. Tsan-Chi Chen, Ting-Yi Wang, San-Fang Chou, Pei-Ting Jain, Shu-Wen Chang*. Moxifloxacin-Causing Suppression of Corneal Myofibroblast Differentiation via Blocking TGF-£]RI Expressions. The 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan, Mar 27-28, 2010.
74. Shu-Wen Chang, Tsan-Chi Chen, Ting-Yi Wang, and Fang-Yi Lin. Moxifloxacin Suppresses Alpha Smooth Muscle Actin Expression in Corneal Fibroblasts. The 2009 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan, Nov 12-15, 2009.
75. Shu-Wen Chang, Tsan-Chi Chen, Ting-Yi Wang, and Jie-Ling Chang. Mitomycin C Inhibits Corneal Fibroblast Migration through Dephosphorylation of FAK/Paxillin Signaling. The 2008 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 29-30, 2008.
76. Shu-Wen Chang, Tsan-Chi Chen, Ting-Yi Wang, and Fang-Yi Lin. Mitomycin C-Treated Corneal Fibroblasts Regulate Corneal Epithelial Migration through HGF Secretion. The 2008 Annual Meeting of the Ophthalmological Society of the Republic of China, Taipei, Taiwan. Nov 29-30, 2008.
77. Tsan-Chi Chen, Yiu-Kay Lai, Chun-Keung Yu, and Jyh-Lyh Juang. Enterovirus 71 triggers apoptosis in neuronal cells through activation of Abl-Cdk5 signaling. Fifteenth Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Pingtung, Taiwan. Feb 1-3, 2007.
78. Tsan-Chi Chen, Yiu-Kay Lai, Chun-Keung Yu, and Jyh-Lyh Juang. Enterovirus 71 triggers apoptosis in neuronal cells through activation of Abl-Cdk5 signaling. 2006 IBC Symposium on Protein Post-Translational Modification, Taipei, Taiwan. Nov 29-Dec 1, 2006.
79. Tsan-Chi Chen, Shih Sheng Jiang, Chao Hsiung, Wei-Chen Chen, Guang-Wu Chen, Shiang-Ming Lin, Jih-hui Lin, Shu-chun Chiu, Yiu-Kay Lai, and Jyh-Lyh Juang. Coupling multiplex RT-PCR to gene chip assay for sensitive and semi-quantitative detection of severe acute respiratory syndrome-coronavirus. °ê¥ß²MµØ¤j¾Ç¥Í©R¬ì¾Ç°|¬ã¾Ç·|²Ä¤@©¡¥Í¬ì¾Ç³N¦~·|, National Tsing Hua University, Hsinchu, Taiwan. Apr 16, 2004.
80. Tsan-Chi Chen, Whei-Meih Chang, and Yiu-Kay Lai. The Expression of HSP70 Family Members in Cadmium-Treated Human Non-Small Cell Lung Cancer H460 Cells. ²Ä¤T©¡®ü®l¨â©¤²Ó­M¥Íª«¾Ç¾Ç³N¬ã°Q·|,Wuhan University, Hubei, China. May 16-18, 2001.
81. ³¯ÀéÄQ, ¹ù¥¿¹F,´¿¬L·ç,¹ù¦³Á÷,Á«ÛùÚ,¬x§Ó»Ê,Áé¥ü¬K,§õ§»ÂÓ. A Food-Borne Outbreak of Gastroenteritis. ²Ä¤C©¡¥þ°êÂå¨Æ§Þ³N¾Ç¨t¾Ç¥Í¬ã¨s½×¤åµoªí·|, Taipei Medical University, Taipei, Taiwan. Mar 29-30, 1996.